Greenville is a city in South Carolina, USA. The city's population in 2012 was 60 709 people, in 2017 it ranks 6th in the list of the most populated cities in the state.
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Geography Greenville is located roughly evenly between Atlanta, Georgia and Charlotte, North Carolina. Climate Greenville has a subtropical oceanic climate, usually with mild, short winters; hot, humid summer; warm spring; and dry autumn.